Tyrosine Supplementation to Improve Physical and Mental Performance - WorkWize

Tyrosine Supplementation to Improve Physical and Mental Performance

Increased dopaminergic and noradrenergic activity in the brain has been associated with feelings of motivation, arousal and reward and decreased fatigue, and this has been linked to enhanced performance.
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Gatorade – Tyrosine Supplementation to Improve Physical and Mental Performance.

The Gatorade Sports Science Institute is investigating performance benefits from Tyrosine supplementation.

Key points from their article:

  • Increased dopaminergic and noradrenergic activity in the brain has been associated with feelings of motivation, arousal and reward and decreased fatigue, and this has been linked to enhanced performance.
  • Both dopamine and norepinephrine are synthesised from the non-essential amino acid tyrosine through a shared metabolic pathway.
  • Since tyrosine and the other large-neutral amino acids (LNAA) share a common transporter across the blood-brain barrier, an elevation in the plasma concentration ratio of tyrosine to LNAA increases tyrosine uptake into the brain.
  • The increased delivery of tyrosine into the central nervous system may result in increased brain dopamine and norepinephrine synthesis, although this relationship may be not straightforward.
  • The current balance of evidence does not support a benefit of ingesting tyrosine to enhance exercise performance, but longer-term studies may be required to reveal a clear response.
  • Tyrosine supplementation does appear to consistently attenuate losses in cognitive function when individuals are exposed to challenging environments. As many sporting situations are highly dependent on effective decision-making and the successful execution of fine and gross motor skills, this would be desirable, despite no apparent benefit to physical performance.

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